Johnson, DavidGannon, Renae2022-02-182022-02-182022-02-18https://hdl.handle.net/1794/27040For continued advancement in materials science, a deeper understanding of structure and interfaces is needed. This is true for a wide variety of materials systems and length-scales. This dissertation focuses on exploring the structure and interfaces of layered heterostructures, thin film compounds, and in multiphase systems such as those in battery stacks where interfaces exist between materials from a wide variety of classes. For layered heterostructures and thin film compounds, interface interactions become increasingly important. This dissertation first explores the use of electron microscopy techniques to investigate formation mechanisms and reaction pathways in layered heterostructures and thin compounds from picometer to nanometer length-scales. Next, failure mechanisms, structure, and interfaces were explored using electron microscopy in layered multiphase materials with components generally used in batteries on nanometer to millimeter length-scales. This dissertation includes previously published and unpublished coauthored material.en-USAll Rights Reserved.Electron microscopyMaterials scienceSolid state chemistryThin filmsElectronic Thesis or Dissertation