Reward abnormalities among women with bulimia nervosa: A functional magnetic resonance imaging study

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dc.contributor.authorBohon, Cara, 1981-
dc.date.accessioned2010-11-30T23:12:52Z
dc.date.available2010-11-30T23:12:52Z
dc.date.issued2010-06
dc.descriptionx, 73 p. : ill. A print copy of this thesis is available through the UO Libraries. Search the library catalog for the location and call number.en_US
dc.description.abstractThe current study measured BOLD brain response using functional magnetic resonance imaging (fMRI) to explore the hypothesis that women with bulimia nervosa have a hyper-responsivity of the mesolimbic reward system. Women with bulimia nervosa and healthy controls (N=24) completed an fMRI paradigm involving anticipated and actual receipt of chocolate milkshake and a tasteless control solution. Women with bulimia nervosa showed less activation than healthy controls in the right anterior insula in response to anticipatory food reward and in the left medial orbitofrontal cortex, right posterior insula, right precentral gyms, and right mid dorsal insula in response to consummatory food reward. Covariates related to bulimia diagnosis accounted for some of these effects, but not all. Results suggest that bulimia nervosa may be related to hypo-functioning of the brain reward system rather than hyper-functioning. Implications for intervention and future research are discussed.en_US
dc.description.sponsorshipCommittee in charge: Jeffrey Measelle, Chairperson, Psychology; Jennifer Ablow, Member, Psychology; Don Tucker, Member, Psychology; Eric Stice, Member, Not from U of 0; William Harbaugh, Outside Member, Economicsen_US
dc.identifier.urihttps://hdl.handle.net/1794/10848
dc.language.isoen_USen_US
dc.publisherUniversity of Oregonen_US
dc.relation.ispartofseriesUniversity of Oregon theses, Dept. of Psychology, Ph. D., 2010;
dc.subjectCovariatesen_US
dc.subjectMesolimbic reward systemsen_US
dc.subjectReward abnormalitiesen_US
dc.subjectBulimiaen_US
dc.subjectNeurosciencesen_US
dc.subjectPsychobiologyen_US
dc.subjectClinical psychologyen_US
dc.titleReward abnormalities among women with bulimia nervosa: A functional magnetic resonance imaging studyen_US
dc.typeThesisen_US

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