Advancing Clinical Natural Language Processing through Knowledge-Infused Language Models

dc.contributor.advisorNguyen, Thien
dc.contributor.authorLu, Qiuhao
dc.date.accessioned2024-01-09T22:16:29Z
dc.date.available2024-01-09T22:16:29Z
dc.date.issued2024-01-09
dc.description.abstractPre-trained Language Models (PLMs) have shown remarkable success in general-domain text tasks, but their application in the clinical domain is constrained by specialized language, terminology, and a lack of in-depth understanding of scientific and medical knowledge. As the adoption of Electronic Health Records (EHRs) and intricate clinical documents continues to grow, the need for domain-adapted PLMs in healthcare research and applications becomes increasingly vital. This research proposes innovative strategies to address these challenges, integrating domain-specific knowledge into PLMs to enhance their efficacy in healthcare. Our approach includes (i) fine-tuning models with knowledge graphs and domain-specific textual data, using graph representation learning and data augmentation techniques, and (ii) directly injecting domain knowledge into PLMs through the use of adapters. By employing these methods, the study aims to improve the performance of clinical language models in tasks such as interpreting EHRs, extracting information from clinical documents, and predicting patient outcomes. The advancements achieved in this work hold the potential to significantly influence the field of clinical Natural Language Processing (NLP) and contribute to improved patient care and healthcare innovation.en_US
dc.identifier.urihttps://hdl.handle.net/1794/29115
dc.language.isoen_US
dc.publisherUniversity of Oregon
dc.rightsAll Rights Reserved.
dc.subjectClinical NLPen_US
dc.subjectKnowledge Integrationen_US
dc.subjectLanguage Modelsen_US
dc.subjectNatural Language Processingen_US
dc.titleAdvancing Clinical Natural Language Processing through Knowledge-Infused Language Models
dc.typeElectronic Thesis or Dissertation
thesis.degree.disciplineDepartment of Computer Science
thesis.degree.grantorUniversity of Oregon
thesis.degree.leveldoctoral
thesis.degree.namePh.D.

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