A Comparison of Robotic Assisted Laparoscopic Prostatectomy and External Beam Radiation Therapy for Urinary and Sexual Function in Men Treated for Prostate Cancer
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Date
2018
Authors
Fischer, Julia
Journal Title
Journal ISSN
Volume Title
Publisher
University of Oregon
Abstract
INTRODUCTION: Prostate cancer is the second most commonly diagnosed cancer in
men. Robot Assisted Laparoscopic Prostatectomy (RALP) and External Beam Radiation
Therapy (EBRT) are standard treatments for clinically localized prostate cancer, but
both of these treatments have negative consequences for urinary and sexual function in
patients.
PURPOSE: To compare changes in urinary and sexual function for men treated with
RALP and EBRT.
HYPOTHESIS: It was hypothesized that patients treated with EBRT would have better
recovery of sexual function, and patients treated with RALP would have better
recovery of urinary function.
METHODS: Urinary and sexual function for patients treated for prostate cancer was
examined using Expanded Prostate Index Composite (EPIC) questionnaires. These
questionnaires were completed before treatment and two years after initial treatment
in 32 men treated with EBRT, and 104 men treated with RALP. The difference between
initial treatment scores and 2-year scores were analyzed with a general linear
model(GLM) procedure to assess the quality of life outcomes for EBRT and RALP.
RESULTS: No significant difference was found for change in urinary function for either
treatment group (p = 0.41). EBRT was found to significantly increase recovery sexual
function compared to RALP (p = 0.04).
CONCLUSION: EBRT is a superior treatment for preserving sexual function in men with
prostate cancer, whereas there is no significant difference in recovery of urinary
function.
Description
23 pages
Keywords
Prostate cancer, Robot Assisted Laparoscopic Prostatectomy, External Beam Radiation Therapy, Sexual function, Urinary function
Citation
Fischer, J. (2018). A Comparison of Robotic Assisted Laparoscopic Prostatectomy and External Beam Radiation Therapy for Urinary and Sexual Function in Men Treated for Prostate Cancer. Oregon Undergraduate Research Journal, 12(1). doi:10.5399/uo/ourj.12.1.2