Language Mapping with Dense Array EEG Source Localization: Implications for Neurosurgical Planning

dc.contributor.advisorTucker, Donen_US
dc.contributor.authorNelson, Josephen_US
dc.creatorNelson, Josephen_US
dc.date.accessioned2012-10-26T04:08:05Z
dc.date.available2012-10-26T04:08:05Z
dc.date.issued2012
dc.description.abstractCurrent language mapping protocols for neurosurgical planning are invasive, expensive, and not suitable for all surgical candidates. We investigated the potential of dense array EEG to determine hemispheric dominance for language and localize current sources of semantic and lower level language functions in the brain using a semantic decision task, a phonological decision task, and an acoustic decision task. Source estimates of N400-window ERPs (N365, N480) and the Late Positive Complex (LPC) localized strongly to medial temporal regions. Overall source estimates revealed a slight left lateralized network, with more posterior engagement for the semantic condition and more anterior engagement for the phonological condition. Source localization of the resulting t-test wave from the semantic - phonological highlighted a stronger left lateralized pattern of activation encompassing more of the semantic network. As a first pass these results are promising, but need to be investigated on individual subject ERPs.en_US
dc.identifier.urihttps://hdl.handle.net/1794/12464
dc.language.isoen_USen_US
dc.publisherUniversity of Oregonen_US
dc.rightsAll Rights Reserved.en_US
dc.subjectEEGen_US
dc.subjectLanguageen_US
dc.subjectLocalizationen_US
dc.subjectMappingen_US
dc.subjectNeurosurgicalen_US
dc.subjectPresurgicalen_US
dc.titleLanguage Mapping with Dense Array EEG Source Localization: Implications for Neurosurgical Planningen_US
dc.typeElectronic Thesis or Dissertationen_US

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