Genome Evolution and Gene Expression Divergence in the Genus Danio

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dc.contributor.advisorPostlethwait, John
dc.contributor.authorMcCluskey, Braedan
dc.date.accessioned2016-10-27T18:43:48Z
dc.date.issued2016-10-27
dc.description.abstractGenus Danio includes zebrafish (Danio rerio) and several other phenotypically diverse species. To understand the history of these species and how they acquired the genetic differences underlying their diverse phenotypes, I performed two phylogenomic studies using Restriction-Site Associated DNA Sequencing and DNA hybridization-based exome enrichment. The results of these studies highlight important methodological considerations applicable to future experiments across taxa. Furthermore, these studies provide detailed understanding of the relationships within Danio including extensive introgression between lineages. The extent of introgression varies across the genome with regions of high recombination at the ends of chromosomes having the most evidence for introgression. Together, this work gives vital insight into the history of a model organism and the evolutionary processes that give rise to phenotypic diversity.en_US
dc.identifier.urihttps://hdl.handle.net/1794/20484
dc.language.isoen_US
dc.publisherUniversity of Oregon
dc.rightsCreative Commons BY 4.0-US
dc.subjectDanioen_US
dc.subjectEvolutionen_US
dc.subjectExomeen_US
dc.subjectLinked selectionen_US
dc.subjectPhylogenomicsen_US
dc.subjectZebrafishen_US
dc.titleGenome Evolution and Gene Expression Divergence in the Genus Danio
dc.typeElectronic Thesis or Dissertation
thesis.degree.disciplineDepartment of Biology
thesis.degree.grantorUniversity of Oregon
thesis.degree.leveldoctoral
thesis.degree.namePh.D.

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