Investigation of the Anion Binding Properties of Tripodal and Arylethynyl-Based Receptors

dc.contributor.advisorDeRose, Victoriaen_US
dc.contributor.authorWatt, Michelleen_US
dc.date.accessioned2014-10-17T16:14:21Z
dc.date.issued2014-10-17
dc.description.abstractAnion sensing is important due to the roles anions play in biological systems and the environment. Given the complexity of these environments, selectivity in receptors is crucial. Research in the labs of Profs. Darren Johnson and Mike Haley focuses on developing novel receptors which use non-covalent interactions to reversibly bind anions—ideally for use in sensors. This dissertation presents novel tripodal-structured receptors, as well as systems based on a previously established arylethynyl scaffold —a conjugated backbone that often provides fluorescent properties to the receptor. Chapter I is an introduction of the less commonly utilized non-colvalent interactions for anion binding—anion–π interactions and Caryl–H hydrogen bonds. The design and synthesis of cryptand and tripodal receptors with electron-deficient arenes ideal for anion–π interactions is presented in Chapter II. Chapters III and IV discuss work on novel tripodal 1,3,5-tris(arylethynyl)benzene receptors which demonstrate either anion–π interactions and Caryl–H···X– hydrogen bonds. A chloride selective bis(urea) arylethynylpyridine receptor is presented in Chapter V. Lastly, Chapter VI introduces initial efforts on the synthesis of mono(urea) arylethynyl receptors which will be used to further explore the anion–π binding capabilities of these systems and may also demonstrate the preference of anion–π binding interactions over Caryl–H hydrogen bonding when binding nitrate, as is demonstrated in Chapters III and IV. This dissertation includes previously published and unpublished coauthored material.en_US
dc.description.embargo2016-10-17
dc.identifier.urihttps://hdl.handle.net/1794/18517
dc.language.isoen_USen_US
dc.publisherUniversity of Oregonen_US
dc.rightsAll Rights Reserved.en_US
dc.subjectAnion Receptoren_US
dc.subjectNon-covalenten_US
dc.subjectSupramolecularen_US
dc.titleInvestigation of the Anion Binding Properties of Tripodal and Arylethynyl-Based Receptorsen_US
dc.typeElectronic Thesis or Dissertationen_US
thesis.degree.disciplineDepartment of Chemistry and Biochemistryen_US
thesis.degree.grantorUniversity of Oregonen_US
thesis.degree.leveldoctoralen_US
thesis.degree.namePh.D.en_US

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