Uncovering the Dynamics of Wolbachia-associated Plastic Recombination in Drosophila melanogaster
| dc.contributor.advisor | Singh, Nadia | |
| dc.contributor.author | Mostoufi, Sabrina | |
| dc.date.accessioned | 2023-07-06T14:11:00Z | |
| dc.date.issued | 2023-07-06 | |
| dc.description.abstract | Wolbachia pipientis is an endosymbiotic bacterium that infects 40%-60% of arthropod species and manipulates the reproduction and fitness of its host. Wolbachia also infects the model fruit fly, Drosophila melanogaster, in a symbiotic host-microbe relationship. Recently, Wolbachia infection was shown to induce plastic recombination in D. melanogaster, but the dynamics of this phenomenon are unknown. In my dissertation work, I investigated how microbe and host affect this phenomenon, in addition to illuminating where this phenomenon occurs across the genome. In Chapter I, I tested the effect of Wolbachia titer on recombination rate and found that bacterial titer did not affect the magnitude of recombination rate increase in Wolbachia-associated recombination. In Chapter II, I examined the effect of Wolbachia infection on transposable element expression in D. melanogaster and compared the effect of Wolbachia to other types of infections. Together, these findings provide a crucial foundation for future work investigating the mechanisms of Wolbachia-associated plastic recombination.This dissertation includes previously published and unpublished co-authored material. | en_US |
| dc.description.embargo | 2023-11-01 | |
| dc.identifier.uri | https://hdl.handle.net/1794/28497 | |
| dc.language.iso | en_US | |
| dc.publisher | University of Oregon | |
| dc.rights | All Rights Reserved. | |
| dc.subject | Bacterial titer | en_US |
| dc.subject | Drosophila melanogaster | en_US |
| dc.subject | Plasticity | en_US |
| dc.subject | Recombination | en_US |
| dc.subject | Transposable elements | en_US |
| dc.subject | Wolbachia pipientis | en_US |
| dc.title | Uncovering the Dynamics of Wolbachia-associated Plastic Recombination in Drosophila melanogaster | |
| dc.type | Electronic Thesis or Dissertation | |
| thesis.degree.discipline | Department of Biology | |
| thesis.degree.grantor | University of Oregon | |
| thesis.degree.level | doctoral | |
| thesis.degree.name | Ph.D. |
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