An Examination of Current Research Exploring the Relationship Between Obesity and Hepatocellular Carcinoma

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Date

2016-03

Authors

Andreason, Teale D.

Journal Title

Journal ISSN

Volume Title

Publisher

University of Oregon

Abstract

Over two thirds of US adults were classified as overweight in 2012. Comorbidities associated with obesity, including hepatocellular carcinoma, (HCC) are pervasive in the US population. Due to the current high prevalence of obesity, a considerable amount of research is actively being done to understand the pathophysiology of such diseases. My intention for this thesis project is to first gain a deep understanding of the complex connection between obesity and increased risk of HCC. I then wish refine my ability to communicate complicated information about these diseases, especially to an audience without a scientific background, in preparation to practice medicine as a Physician Assistant. To accomplish these goals, I will first present a literature review of recently published, peer-reviewed journal articles examining the relationship between obesity and HCC. I will then deliver a lecture, entitled "The Relationship Between Obesity and Cancer," to fellow undergraduate students in 81123, Biology of Cancer at the University of Oregon. Alan Kelly is the instructor for the course, which has approximately 190 students enrolled. The content of fifty-minute lecture is to be derived from information collected from the literature review. The lecture materials and DVD recording are to be included in this thesis.

Description

51 pages. A thesis presented to the Department of Biology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2016.

Keywords

Human physiology, Biology, Obesity, Hepatocellular carcinoma, Cancer, Liver, NAFLD, Steatosis

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