Using Zebrafish Models of Usher Syndrome Type 2A to Investigate Retinal Cell Function and Survival
| dc.contributor.author | Lerner, Kimberly | |
| dc.contributor.author | Phillips, Jennifer B. | |
| dc.contributor.author | Westerfield, Monte | |
| dc.date.accessioned | 2015-06-10T01:02:37Z | |
| dc.date.available | 2015-06-10T01:02:37Z | |
| dc.date.issued | 2015 | |
| dc.description | Single page poster | en_US |
| dc.description.abstract | Usher syndrome is the most common cause of hereditary deaf blindness and has no cure. Mutations in the USH2A gene, which encodes the protein Usherin, are responsible for Usher syndrome type 2A (USH2A). Patients diagnosed with USH2A have congenital hearing impairment that ranges from moderate to severe and experience progressive vision loss beginning in the second decade of life. This progressive vision loss, called retinitis pigmentosa (RP), is due to degeneration of the photoreceptor cells in the retina, which initially causes night blindness and progresses to tunnel vision. We are investigating retinal symptoms of USH2A using a zebrafish disease model. | en_US |
| dc.identifier.uri | https://hdl.handle.net/1794/18928 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | University of Oregon | en_US |
| dc.rights | Creative Commons BY-NC-ND 4.0-US | en_US |
| dc.subject | Usher Syndrome | en_US |
| dc.subject | Zebrafish | en_US |
| dc.subject | Retinal cell function | en_US |
| dc.subject | USH2A | en_US |
| dc.subject | Retinitis pigmentosa | en_US |
| dc.title | Using Zebrafish Models of Usher Syndrome Type 2A to Investigate Retinal Cell Function and Survival | en_US |
| dc.type | Other | en_US |