A Meta-Analysis of Hippocampal and Amygdala Volumes in Patients Diagnosed With Dissociative Identity Disorder

dc.contributor.authorBlihar, David
dc.contributor.authorCrisafio, Anthony
dc.contributor.authorDelgado, Elliott
dc.contributor.authorBuryak, Marina
dc.contributor.authorGonzalez, Michael
dc.contributor.authorWaechter, Randall
dc.date.accessioned2023-07-31T21:21:45Z
dc.date.available2023-07-31T21:21:45Z
dc.date.issued2021-01-12
dc.description14 pagesen_US
dc.description.abstractDissociative Identity Disorder (DID), an illness characterized by multiple personality states, has long been a controversial diagnosis within the psychiatric community. Demonstrating a neuroanatomical basis for the disorder may help to resolve the controversy. Current literature on the neuroanatomy associated with DID has focused on the hippocampus and amygdala and are inconclusive. This meta-analysis pools the results from n = 3 studies to compare the mean size of these two structures between DID patients, non-DID patients, and healthy controls. Patients diagnosed with both DID & PTSD were found to have smaller hippocampi bilaterally (p< .001) compared to healthy controls; no significant difference was seen in the amygdala. When comparing DID to PTSD patients, the left hippocampus was smaller (p< .001), with a trend for a smaller right hippocampus (p = .06). A comparison of the amygdala was not possible due to a lack of data. These findings suggest that a smaller hippocampus is seen in DID patients beyond what is seen for PTSD, provides neuroanatomical evidence for the memory impairment often seen in DID patients (i.e., amnesia experienced by the host and alters), and presents a potentially novel means to understand this disorder.en_US
dc.identifier.citationDavid Blihar, Anthony Crisafio, Elliott Delgado, Marina Buryak, Michael Gonzalez & Randall Waechter (2021) A Meta-Analysis of Hippocampal and Amygdala Volumes in Patients Diagnosed With Dissociative Identity Disorder, Journal of Trauma & Dissociation, 22:3, 365-377, DOI: 10.1080/15299732.2020.1869650en_US
dc.identifier.doihttps://doi.org/10.1080/15299732.2020.1869650
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/15299732.2020.1869650
dc.identifier.urihttps://hdl.handle.net/1794/28628
dc.language.isoenen_US
dc.publisherTaylor & Francis Groupen_US
dc.rightsCreative Commons BY-NC-ND 4.0-USen_US
dc.subjectDissociative Identity Disorder (DID)en_US
dc.subjectmultiple personality disorderen_US
dc.subjectMRIen_US
dc.subjectneuroanatomyen_US
dc.subjecthippocampusen_US
dc.subjectamygdalaen_US
dc.titleA Meta-Analysis of Hippocampal and Amygdala Volumes in Patients Diagnosed With Dissociative Identity Disorderen_US
dc.typeArticleen_US

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