DISSOCIATIVE DISORDERS IN JAPAN: A PILOT STUDY WITH THE DISSOCIATIVE EXPERIENCE SCALE AND A SEMI-STRUCTURED INTERVIEW Masahiro Umesue, M.D., Ph.D. Tadashi Matsuo, M.D., Ph.D. Noboru Iwata, Ph.D. Nobutada Tashiro, M.D., Ph.D. Masahiro Umesue, M.D., Ph.D., is a psychiatrist in the Department of Psychiatry at National Kyushu Medical Center Hospital in Japan. Tadashi Matsuo, M.D., Ph.D., is a lectur- er in the Department of Neuropsychiatry at Kyushu University, Japan. Noboru Iwata, Ph.D., is an Assistant Professor at the Institute of Industrial Ecological Sciences at University of Occupational and Environmental Health, in Japan. Nobutada Tashiro, M.D., Ph.D., is Professor of Neuropsychiatry at Kyushu University. For reprints write Masahiro Umesue, M.D., Ph.D., Depart- ment of Psychiatry at National Kyushu Medical Center Hospital 1-8-1, Jigyo Chuouku Fukuotca, 810, Japan. A part of the study was presented at 12th International Fall Conference of the International Society for the Study of Dissociation which was held in Lake Buena Vista, Florida in September 1995. ABSTRACT A Japanese version of the Dissociative Experiences Scale (]DES) was developed and administered to 199 late adolescents, 40 normal adults, 16 schizophrenics, and 19 subjects with dissociative disor- ders whose diagnoses were made with a comprehensive assessment including a semi-structured interview. As a result, theJDES yield- ed comparable reliability and validity with those established for the Dissociative Experience Scale in North America. Of 19 with disso- ciative disorders, one was identified as multiple personality disorder (MPD fDSM-Wname change: dissociative identity disorder]) and eight were identified as dissociative disorder not otherwise specified (DDNOS). A large percentage of those with DDNOS had partial symp- tomatic profiles of MPD except for identity disturbance. The distri- bution of J-DES scores suggested that the concept of a dissociative continuum is cross-culturally applicable, although the presentation of dissociative disorders may be influenced by the Japanese cultural background. INTRODUCTION During the past decade there has been a rapid increase in the number of case reports and publications about dis- sociative disorders, especially of multiple personality disor- der (MPD [ DSM-IV name change: dissociative identity disor- der]) mainly in North America (Bliss 1986; Kluft 1987; Coons, Bowman, Kluft, Milstein, 1991; Putnam 1991; Goff Simms 1993). On the other hand, there is much skepticism about the dissociative disorders as distinct diagnostic categories, particularly about MPD (Dell, 1988; Fahy, 1988; Merskey, 1992). Some critics have suggested that the increase in case reporting of MPD reflects iatrogenic and cultural influences on suggestible patients in North America (Fahy, 1988; Fahy, 1992; Merskey, 1992). There have been very few case reports on MPD in japan, although the first Japanese case of MPD was reported in 1919 (Nakamura, 1919). Ichimaru identified only five cases ofMPD in the Japanese literature between 1919 and 1992 (Ichimaru, 1993). Takahashi reviewed and diagnosed 489 inpatients uti- lizing DSM-I1I or DSM-III-R criteria and found no case ofMPD (Takahashi, 1990). His study has been criticized for its methodology. It used no structured diagnostic instruments and failed to control for skeptical bias among Japanese psy- chiatrists (Ross, 1990). There have been several studies using the Dissociative Experience Scale in Japan (Tanabe Ogawa, 1992; Berger, Ono, Nakajima, Suematsu, 1994; Berger et al. 1995) , although validation of the scale in Japanese populations had not been established with a clinical population of dissocia- tive disorders. The present study was designed to clarify the character- istics of dissociative disorders in japan. We developed a Japanese version of the DES(j-DES) and validated it using a clinical population of dissociative disorder patients diagnosed on the basis of a comprehensive assessment including a semi- structured interview. METHODS Subjects The study subjects consisted of four groups: 199 late ado- lescents, 40 normal adults, 16 subjects with schizophrenia, and 19 subjects with dissociative disorders. The late adolescent subjects were undergraduate students at Kyushu University. They were from health science classes and volunteered to participate in the study. The normal adult subjects were staff members at a private psychiatric hospital 182 DISSOCIATION, Vol. IX, No. 3, Septcmberl996 UMESUE/MATSUO /IWATA/TASHIRO and volunteered to participate in the study. All clinical subjects were outpatients of Kyushu University Hospital. Twenty-two subjects had been referred consecu- tively to the authors by several colleagues for evaluation of dissociative states; 19 subjects met criteria for dis- sociative disorders. The remaining three subjects received a DSM-III-Rdiagnosis of post-traumatic stress disorder, obses- sive-compulsive disorder, and dysthymic disorder, respec- tively, and were excluded from the study. Sixteen subjects with schizophrenia were the first available patients with this diagnosis within the time limit of the study. The meanD age of the 199 late adolescents and the 40 normal adults were 18.6.9 (range = 18-21) and 37.8.0 years (range = 23-54), respectively. Of 199 late adolescents, 168 (84%) were men and 31 (16%) were women. Of 40 nor- mal adults, 21 (53%) were women and 19 (48%) were men. The meanD ages of the subjects with dissociative disorders and with schizophrenia were 24.7.5 (range = 17-59), and 34.60.6 years (range = 14-54), respectively. Of the 19 sub- jects with dissociative disorders, 10 (53%) were men and 9 (47%) were women. Of the 16 subjects with schizophrenia, 8 (50%) were men and 8 (50 %) were women. Instruments The structured clinical interview forDSM-III-RDissociative Disorders (SCID-D) is a diagnostic instrument developed for the assessment of five dissociative symptom areas (amnesia, depersonalization, derealization, identity confusion, and identity alteration) and for the diagnosis of the dissociative disorders (Steinberg, 1993; Steinberg, 1993; Steinberg, Cicchetti, Buchanan, Rakfeldt, Rounsaville,1994). It has proven utility in confirming known cases of dissociative dis- orders as well as in detecting unknown cases of dissociative disorders cross-nationally (Steinberg et al., 1990; Boon Draijer, 1991); With reference to SCID-D, we conducted a semi-structured interview and rated each five dissociative symptom according to the severity rating definitions of SC1D- D: absent, mild, moderate, or severe (Steinberg, 1993). The Dissociative Experience Scale (DES) is a 28-item visu- al analog self-report scale that was developed to quantify dis- sociative experiences in normal and clinical populations (Bernstein Putnam, 1986). The subject indicates how often he or she has had the experience described in the question by making a slash on a 100-mm line. The DES has been the most widely used and studied instru- ment in the dissociation research field for which reliability and validity have been reported by several investigators (Bernstein Putnam, 1986; Ross et al.,1988; Dubester Braun, 1995). Making of theJ-DES was accomplished as fol- lows. First, the original DES items were translated into Japanese by the authors and checked by several senior psy- chiatrists. This version was then back-translated blindly into English by a professional translator. Dr. E. B. Carlson, the first author of the DES, was asked to compare these two English versions to confirm the content of the Japanese ver- sion. Only a few minor difficulties were identified through this process and it was then modified to obtain a better trans- lation. Then, a pilot field trial was conducted with the pre- liminary version of the J-DES using normal adults and late adolescents. A few ambiguous points were identified through this process, and then wording was modified to ensure that the questions were understood more clearly. The final form ofj-DES contains the same 28 items as orig- inalDES. However, we modified the directions cover sheet. The original directions specify that the questions only apply to those experiences that are not associated with the use of alcohol or drugs. We deleted drugs conditions from the directions, because drug problems appear less prevalent among Japanese. Diagnosis To reach DSM-III-R lowing procedures were conducted to meet the LEAD stan- dard proposed by Spitzer (1983). Twenty-two subjects con- secutively referred to the authors for evaluation of dissociative states received the aforementioned semistructured interview; chart reviews were also conducted. On the basis of a com- prehensive assessment of all available data, the diagnoses were made by one of the authors and then were confirmed by one of the other authors. These procedures were carried out blind to the results of the J-DES. The DSM-III-Rdiagnoses for schizophrenia of the 16 sub- jects were made respectively by the subjectstreating psy- chiatrists and then were confirmed by one of the authors. Data Collection The J-DES was administered in three different settings. For late adolescents, theJ-DES was administered to 199 under- graduate students in a classroom setting. The was then readministered to 133 of the 199 undergraduate students after an interval of four weeks. For normal adults, the was administered individually, after the first author inter- viewed them personally and confirmed that they were well adapted to their place of work and had no evidence of men- tal disorders. For the subjects with dissociative disorders, the J-DES was administered by one of the authors after the semi- structured interview was conducted. For the subjects with schizophrenia, their treating psychiatrist administered the J-DES in their individual sessions. An informed consent was obtained from all subjects after the study procedure was fully explained. Data Analyses The score for each item and the overall score of theJ-DES for each subject were measured using the method of Bernstein and Putnam (1986). Scores for each item were determined by measuring the subject slash mark to the near- est left-hand 5 mm anchor point of the 100 mm line. The 183 DISSOCIATION, Vol. Iii, No. 3, Septemherl9% DISSOCIATIVE DISORDERS IN JAPAN score for the entire scale is an average of the 28-item scores. It will be referred to as the J-DES score. Non-parametric statistical methods were applied to ana- lyze data whenever possible, because the distribution of J- DES scores within the studied population is not known. RESULTS Diagnosis and Clinical Profiles of Dissociative Disorders Nineteen subjects with dissociative disorders were classi- fied into five diagnostic categories. The (Axis I) diag- noses for these subjects are presented in Table 1. Although dissociative disorder not otherwise specified (DDNOS) is a residual category of dissociative disorder in a large part of the DDNOS subjects reported high levels of dissocia- tive symptoms except for identity disturbance on SLID-D sever- ity rating definitions. Of the DDNOS subjects, six (75%) reported moderate to severe psychogenic amnesia, and six (75%) reported moderate to severe depersonalization and/or derealization. On the contrary, of the DDNOS sub- jects, only one (12.5%) reported moderate identity alteration, and two (25%) reported moderate to severe identity confu- sion. No alternate personalities or distinct personality states were observed among the DDNOS subjects. Of the 19 subjects with dissociative disorders, one met the full DSM-III-R criteria for MPD. He had no history of contact with psychiatric professionals prior to this study. His clinical presentation was conforming to MPD symptomatic profiles in North America except for severe amnesia for important personal information. TABLE 1 Diagnostic Subcategories for 19 Subjects with Dissociative Disorders Frequency Subcategories N % Psychogenic amnesia 2 10.5 Psychogenic fugue 3 15.8 Multiple personality disorder 1 5.3 Depersonalization disorder 5 26.3 Dissociative disorder not otherwise specified 8 42.1 TABLE 2 Split-Half Reliability Coefficients for Japanese Version of the Dissociative Experience Scale Group Split Half p N Normal adults 0.94 <0.0001 40 Late adolescents 0.94 <0.0001 199 Schizophrenia 0.91 0.0011 16 Dissociative disorders 0.82 0.0029 19 FIGURE 1 Distribution of Japanese Version of the Dissociative Experience Scale (J-DES) Score by Groups; Normal . Adults (N=40), Schizophrenia (N=16), Late Adolescents (N-199), and Dissociative Disorders (N=19). Boxplot shows 10%, 25%, 50% (median), 75%, and 90% of the J-DES Score Distribution of Each Population Respectively 60 30 0 20 10 50 - 40 - 4 s (Q~- ~~oa~ .y ova o cc s 184 DISSOCIATION. Vol. IX.No.3, Septemberl996 UMESUE/MATSUO/IWATA/TASHIRO Reliability of thef-DES Test-retest reliability of IDES using Spearman rank order cor- relations for 133 late adolescents over a four-week interval was 0.88 (p < 0.001). The internal consis- tency was examined at four levels: split-half reliability coefficient, Cronbach s alpha coefficient, and corrected item-total correlations. Split-half reliability coefficient was calculated using the Spearman- Brown formula. Table 2 presents split half reliability coefficients for each group. They ranged from 0.82 to 0.94. Cronbach alpha coefficient for J-DES score was 94 N 27 ). l bil y o ffi- Validity of theJ-DES All the subclassifications of dissociative disorders were grouped together as dissociative disorders to compare them with other groups, given the small number of the subjects with dissociative disorders. Figure 1 shows a distribution of J-DES scores for each group. The highest median scores were obtained by subjects with dissociative disorders and the low- est median scores were obtained by normal adults. A Kruskal- Wallis test demonstrated that)-DES score significantly differed across the groups (chi-square = 62.94, N = 274, df = 3, p < 0.0001) . Pairwise comparisons by Scheffes test revealed that all but one pair yielded significant difference in the score (Table 3). Spearman rank-order correlation between J-DES scores and age was - 0.11 (p = 0.059, N = 274). A Man-Whitney U- test revealed no significant differences on the J-DES scores between sexes (p = 0.59, N = 274). f-DES Scores Among the Subclassifications of Dissociative Disorders The median J-DES score for each subclassification of dis- sociative disorders is presented in Table 4. A Kruskal-Wallis test demonstrated thatJ-DES score significantly differed across the subclassifications of dissociative disorders (chi square -- 13.3, N = 19, df = 4, p = 0.0098). Pairwise comparisons of each subclassification score were then performed by Scheffe test, yielding the results in Table 4. Subjects with DDNOS obtained the highest group median score and sub- jects with depersonalization disorder obtained the lowest group median score (Table 4). The subject with MPD in this study obtained the relatively lower J-DES score of 32.3 than group median score of DDNOS. DISCUSSION The present study provides sufficient evidence of the reli- ability and validity off-DES. It has excellent test-retest relia- bility, corrected item-total correlations, and split-half relia- bility as well as an excellent Cronbach s alpha coefficient. These findings replicate the high degree of reliability of DES that was demonstrated by previous studies conducted in North America (Bernstein Putnam, 1986; Ross et al., 1988; Frischholz et al., 1990). This study established criterion-ref- erenced validity by providing the evidence that J-DES scores agree with the criteria ofDSM-IIIR dissociative disorder diag- nosis.However, the composition of the subjects with disso- ciative disorders included in this study was totally different from that of the previous studies in North America. The cri- terion-referenced validity of DES in North America has most- ly been established by subjects with MPD (Bernstein Putnam, 1986; Ross et al., 1988; Frischholz et al., 1990), but our study of 19 subjects contained only one with MPD. However, our method for establishing criterion-referenced validity is appropriate to original design of DES, because it was developed to measure dissociation not only in MPD but also in normal and clinical populations (Bernstein Putnam, 1986) . Notwithstanding the divergence of the subjects com- position, this study showed good criterion-referenced valid- ity ofJ-DES. These facts strongly indicate that }DES is a cross- culturally reliable and valid instrument to measure dissociation. The distribution of J-DES scores demonstrates the over- lapping continuum of dissociative experiences across groups and shows a stepwise increasing median J-DES score for each group (Figure 1). This finding also tends to replicate the pre- vious studies with DES (Bernstein Putnam, 1986; Ross, et al. 1988; Coons, et al. 1989). The consistency of responses to the scale between Japan and North America indicates that "dissociative phenomena exist on a continuum and become 185 cients of the corrected item-total score were ranged 0.54 to 0.79, with a median of 0.73, and all of these values reached a level of significance at p < 0.001 (N = 274). TABLE 3 Post-hoc Pairwise Comparisons by Group Normal Adults Schizophrenia Late Adolescents Dissociative Disorders Median score 1.88 6.61 11.78 38.03 Normal adults ** Schizophrenia n.s. Late adolescents *p< .001 . 0001 DISSOCIATION, Vol. IX, Nn. 3. Septemberl996 DISSOCIATIVE DISORDERS IN JAPAN TABLE 4 Post-hoc Painvise Comparisons of the Japanese Version of the Dissociative Experience Scale Among Dissociative Disorders Subjects Depersonalization Disorder Psychogenic Amnesia Multiple Personality Disorder Dissociative Psychogenic Not Otherwise Fugue Specified Median score 17.5 25.3 32.3 37.0 49.0 Depersonalization disorder n.s. n.s. n.s. p=0.024 Psychogenic amnesia n.s. n.s. n.s. Multiple personality disorder n.s. n.s. Psychogenic fugue n.s. maladaptive only when they exceed certain limits in inten- sity or frequency, or occur in inappropriate contexts" (Putnam, 1989, p. 9); namely the concept of a dissociative continuum (Hilgard, 1977; Bernstein Putnam, 1986; Put- nam, 1989) is cross-culturally applicable in japan. The distribution of J-DES scores for the subjects within the dissociative disorders differs somewhat from earlier findings in North American literatures. In previous studies MPD subjects obtained considerably higher scores than DDNOS or any other subject group, and scores above 40 on DES were strongly suggestive of MPD (Coons et al., 1989; Armstrong Loewenstein, 1990; Carlson Putnam, 1993) . These earlier findings are consistent with the theoretical assumption thatMPD is regarded as the most severe model of dissociative process (Confer Ables, 1983; Ross, 1985; Kluft et al.,1988; Putnam, 1989; Ross et al., 1992). In con- trast, the present study demonstrates that the subjects with DDNOS obtained the highest group median score of over 40 on J-DES among the subjects with dissociative disorders. Berger et al. (1994) reported that six of 39 female sub- jects with eating disorder in Japan obtained the DES score over 30 and concluded that this finding reflected a high like- lihood of MPD and post traumatic stress. In their study, nei- ther a structured interview nor an unstructured interview was conducted to determine if patients had a diagnosis of dis- sociative disorders or post-traumatic stress disorder. Moreover, they simply applied norms that had been estab- lished in North America towards the Japanese population, and this might have led to unjustified interpretations. The mere translation of a psychometric instrument is insufficient to make it applicable for use in populations from different linguistic and cultural backgrounds (Flaherty et al.,1988; Iwata et al., 1993; Rogler, 1993; Iwata et al., 1995). This study suggests that a high score on J-DES does not necessarily asso- ciate a high likelihood of MPD in Japan. The present study revealed that a large part of our DDNOS subjects had a resemblance to typical clinical pro- files of MPD in North America except for identity disturbance, and particularly for identity alteration. This suggests that dis- parity of MPD incidence between Japan and North America is fairly attributable to the difference in existence of identi- ty alteration. However, the importance of identity alteration cannot be dismissed, because the core feature of MPD is the existence of alter personalities (Putnam, 1989; Steinberg, 1995). In relation to cross-cultural differences about dissociative disorders, Adityanjee et al. (1989) noted that the pathoplastic influence of the cultural background may be important in developing clinical presentation of dissociative disorders regarding the current status of MPD in India. From a social constructionist view, Martinez-Taboas (1995) noted that cul- ture and consciousness make each other up and he argued that MPD will be fairly visible in societies with an individual- istic outlook of the self. It should be possible to discuss the psychological char- acteristics of a people or the culture with the language it speaks (Whorf, 1956), because clinical psychiatry is based on the assumption that it is possible to get to know a patient s mental state via the words that he uses (Doi, 1973). Suzuki (1978), aJapanese sociolinguist, investigated the use of terms for self-reference in Japanese. He defined Japanese terms of self-reference including all the words with which the speak- er refers to himself. He found that the first-person pronouns constitute only a small portion of self-references in Japanese. Not only that, there is a definite tendency to avoid their use as often as possible. Instead of using first-person pronouns, 186 DISSOCIATION, WAX, No. 3, September1996 UMESUE/MATSU TASHIRO Japanese tend to use kinship terms, position terms, occu- pational titles, and so forth depending on a given social and inter-personal context. On the contrary, in English, terms for self-reference are almost exclusively limited to first-per- son pronouns. The use of terms for self-reference can be interpreted as the speaker act of identifying his status or role linguistically. Self-designation in Japanese is relative and other-oriented in comparison with the absolute type of self designation in English (Suzuki, 1978). Relevant to this point, Kirmayer (1991) noted thatJapanese socialization inculcates a strong sense of interdependence and responsibility for the feelings of others" (Kirmayer, 1991, p. 22). Doi describes a "two-fold or even multifold structure of consciousness" (Doi, 1973; Doi, 1986) in Japanese adaptive psychological functioning. He states: "it doesn blemish a person integrity to take recourse to one or the other depend- ing upon the particular situation he finds himself in" (Doi, 1973, p. 259) . Furthermore he points out that the ease with which one switches one attitude from one situation to anoth- er situation and back again without much strain is regarded as the measure of one social maturity in Japan (Doi, 1973; Doi, 1986). As these quotations suggest, the meaning of an integrated self is different in Japan compared with that in North America. In Japan, a sense of self-designation is rela- tive and pliable, and an awareness of self is covert in its cul- tural context (Tashiro, 1994). Accordingly, it might be rea- sonable to assume that a person who develops severe dissociative symptoms is prone to manifest himself as DDNOS rather than MPD in japan. However, another hypothesis might be possible. The avoidance of first person self-references and the two-fold or even multifold structure of consciousness as cultural norms in japan might combine to appear .so similar to mild forms of MPD as to obscure the recognition of MPD in a culture accustomed to accept the former as normative. This might contribute to a possible systematic bias in our subjects responses to questions (e.g., SCID-D and J-DES) about iden- tity developed by North American researchers for North American subjects. Kirmayer concisely puts it (1991, p. 26): "the recognition of symptoms and syndromes is always selec- tive and based on preconvinced culturally shaped notions (of both patient and physician) as to what is deviant, prag- matically relevant, and worthy of medical attention." In spite of those cultural differences, this study detected one MPD subject in a relatively small group of subjects. This finding provides the evidence that MPD is not a culture-bound syndrome that is defined as "a collection of signs and symp- toms (excluding notions of cause) which is restricted to a limited number of cultures, primarily on the basis of their psychosocial features" (Prince Tcheng-Larouche, 1987, p. 6). Potential limitations of this study should be acknowledged. The subjects with dissociative disorders in the study were referred outpatients for evaluation of dissociative states. Thus, dissociative disorders subjects with subtle dissociative symp- toms might be underrepresented in this study. Further stud- ies are recommended to examine our findings in an unse- lectedgroup of subjects. In addition, this study does not focus other parameters of dissociative disorders than symptoma- tology, such as, etiology, clinical course, and response to treat- ment. These points may well be left to further investigation. 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