'i.J 'f II II i Ii I I f l' Ii ' I, I I I ,] " , , 'I : I ! , 21. April 19, 1928, intestinal obstruction due to urn· bilical hernia. 22. April 26, 1928, heriotomy, right inguinal. 23. May 14, 1928, exploratory laperotomy. 24. May 21, 1928, appendectomY. 25. May 28, 1928, general peritonitis. 26. May 28, 1928, subhepatic abscess. 27. June 11, 1928, herniotomy, inguinal. 28. June 11, 1928, herniotomy, umbilical and in· guinal recurrence. 29. June 5, 1928, ruptured ,gallbladder. 30. June 16, 1928, ruptured gallbladder. . Metropolitan Press, Seattle 1 +·-----,-------------~I TORSION OF THE SPERMATIC CORD WITH GANGRENE MILLARD S. ROSENBLAIT, M. D. Portland, Oregon '.~: , Reprint from The Medical Sentinel, July, 1929 I· .:--0--------------..0-'-'-0-0-0-0-0-0-0-'-0-0....:,::" ;;('.( ' ,,' - - it took another 1/6 grain to give re- lief. The patient was operated on at 8:30 A. M., - three hours after first being seen. Diagnosis: Torsion of sper- matic cord. Operative Record: Orchidectom.y with excision of three inches of spermatic cord. A three-inch right inguinal incision made. Tumor of scrotal sac delivered, found to be a testicle which had be- come twisted on its cord, twist extend- ing all the way to the internal inguinal ring. The testicle was already partly gangrenous. Cord was also gangrenous to the level of the internal ring. The veins of the cord were very tortuous and full. Testicle and cord were removed at the level of the internal ring. Veins, arteries and cord were ligated sepa- rately. Repair of the muscle and fascia were done just as for inguinal hernia. Dermal sutures for skin. Pathological Report (by Dr. Manlove) Gross: The specimen is a much en- larged spermatic cord and testicle. The external surfaces are hemorrhagic. The cord when cut shows diffuse necrotic process t h r 0 ugh 0 u t with hemor- rhage into the tissue. The testicle is brown with a red tinge.. The entire tes- ticle shows disintegration from strangu- lation of the blood supply. Diagnosis: Necrosis of spermatic cord with associated disintegration of testicle from strangulation of blood sup- ply. Torsion of spermatic cord. Clinical Course: The patient was dis- charged, well, from the hospital two weeks after the operation. The pathological physiology in this reported case seems to be the one we have suggested, for there was abnormal mobility, plus varicocele, plus sudden straining. Treatment, unless spontaneous un- twisting occurs at once, incision should be made, and if in the early hours, un- twisting may be sufficient to relieve the condition. If gangrene is present or imminent, orchidectomy is necessary. This case was of 12 hours duration I I I ~~-_.~ Necrosis of Spermatic Cord and Testicle from Torsion. ed. There are acute and occasionally Uffreduzzi has found that a normally recurring cases. attached testis could not undergo tor- The onset has been associated with sion. He felt that the contraction of violent exertion, sudden strain, strain- the cremasteric muscle is responsible for ing at stool, trauma, sudden crossing of the rotation of the cord. Venous con- the leg, coughing, rapid walking, squeez- gestion, be it at the time of puberty, ing, reduction of strangulated hernia. . or at other times, due to varicocele, plus T~ ORSI~ON-OF THE SPERMATIC COR·Di abnormal mobility, plus sudde~ exer-tIon, appears to be the most lOgIcal ex- WITH GANGRENE plan~tion of ~he pa~hologic~l physiol-ogy Illvolved III causmg torsIOn. Differential Diagnosis: The chief points to be differentiated are epidydi- mitis, orchitis, strangulated hernia. Case report of patient treated at the Good Samaritan Hospital: L. B. L. Chart No. 0, 7806. History: A white, adult male, mar- ried, who is 40 years of age. He had been in good health, except for several days prior to the onset of the present illness when he had been very consti- pated and had complained of vague gen- eralized abdominal pain. The evening before the onset of his acute pain the patient had given himself an enema, and while straining excessively at stool had a very sudden, sharp pain in the right testicle. This pain was excruciating in character, and was not relieved. The patient applied very hot compresses and certain essential oils to relieve the pain, but only succeeded in burning the skin of the parts. Although the pain was unrelieved, the patient did not call for medical aid until 5 :30 A. M., some nine hours after the onset of the acute pain. At this time he described the pain by saying that he felt as though someone was "kicking him there all the time." There was a venereal history of gonor- rhea and chancre some 15 years prev- ious to this illness. The pain had been so severe that the patient had vomited clear fluid three or four times. Physical Examination: A thin, but well nourished male, apparently in great distress, writhing in agony from the pain. Examination is negative except for the local condition. The right tes- ticle is two and one-half times normal size, extremely tender and very painful. The spermatic cord is hard as high up ~s it can be felt. The external inguinal ring is small and there is no bulging on coughing. No hernia is present. The skin over the scrotum and lower in- guinal region is burned from the pa- tient's applications; 1/4 gr. morphine- sulphate did not relieve the pain. and MILLARD S. ROSENBLATT, M. D., Portland, Oregon THE ~rst case of torsion. of t~e sper- Sev~ral have been reported as occurringmatIc cord was descnbed m 1840 .durmg sleep.by D~lassiua(Ve. Wallenstein re- The symptoms associated with the on- ports 150 cases in the Journal of Urol- set of this condition are sudden and ogy, for February, 1929, which he has very sharp pain, nausea and vomiting, summarized from the literature, includ- fever, leukocytosis, plus the local symp~ ing one case of his own. Sixteen addi- toms of swelling and extreme tender- tional cases have been found in the liter- ness. ature by us, which are not referred to The recurrent type is described in by Wallenstein. which the symptoms are more mild and. In this group of cases it was found there is spontaneous untwisting. Under that torsion is especially prevalent in etiology, abnormal mobility is considered undescended testis. Of 150 cases, 60 per a cause. A portion of these cases have cent were on the right side and 40 per occurred at puberty and it has been sug- cent on the left side; eight cases of gested that venous congestion at this intra-abdominal testis have been report- time might be a factor. \ ! \ , f author's case at time of operation. th endometrial new growth at lower th the incision made at recent opera- bw growth is shown in inset. Bleeding ~ure of the blebs at the menseS. 'w commenced a dull generalized lower lssociated with tenderness in the lower ~ve scar, and increasing with' each men- e months later there appeared gradually ,dular thickening in this region which ~mall quantities of darkish blood-stained :enstrual period. ncreased in amount, and at present the bleeding requires that her sanitary nap- !'lard in order to absorb the flow from l as from the vagina. The flow is fre- Lse but always dark in color. The tender- the menses is described as excruciating. ination (second day of menstrual period) fler distorted midline scar from symphy- fle condition of the scar is suggestive of infection. At the lower pole, immediately ;is, there is a wrinkled depressed area, ~red, and about the size of a five cent repressions are filled with what appears :\d. A sanitary napkin, the upper end of area, is quite profusely blood-stained. )od from this depressed surface, which ,r and deeply indurated, reveals three blebs in various stages of distention. The largest was ruptured by a probe in the course of the examination and its thick chocolate colored contents ex- truded. A probe can not be inserted without the use of undue force. Vaginal examination reveals a small fluctuant tumor in the region of the right ovary, thought to be an ovarian cyst, and a fundus of normal size in fair anterior position and quite fixed, giving the impression of definite adhesion to the anterior abdominal wall. Preoperative diagnosis: Endometrioma of abdominal wall, fundus adherent to anterior abdominal wall. Right cystic ovary (possibly chocolate cyst). ' Operative report: At operation (eleventh postmenstrual day) the scar was excised, and the pelvic viscera were exposed. A firm cord-like adhesion was noted, extending from the peritoneal aspect of that part of the abdominal HOMER P. RUSH, M.D. PORTLAND, ORE. ADMINISTRATION OF DIGITALIS* Reprint from Northwest Medicine, Seattle, Vol. XXVIII, No. 12, Page 56'2, December, 1929. • Read before the Klickitat and Snohomish County Medical Society, Everett, Wash., Oct. 17, 1929. Digitalis has been known to medical science since it was brought to its attention in 1785 by William Withering. Although that is approximate- ly a hundred and forty years ago, we have yet no drug which can replace it in the treatment of heart disturbances. The history of digitalis is a most in- teresting story. Perhaps its most interesting phase is the correctness of the first observation which, though discredited during much of the early work, has finally been proven to be correct. For therapeutic application digitalis has been prepared in many different ways. The strength and assay of these preparations varied greatly, and as a result dosage was difficult. It was not until 1918 that standardization of digitalis became uniform. Since this time, however, the U. S. P. tinctures or the powdered leaf can be depended upon for assay. It is no longer necessary to use special prepara- tions which are much more expensive to the car- diac patient. The actions of digitalis upon the animal organ- ism are many. These are all less or secondary to its effects upon the heart. This action, which is usually that of increasing the strength yet slowing the beat, is due to a combination of effects. Both vagal stimulation and direct action upon cardiac musculature play their roles in producing this heart • From the Department of Gynecology, University of Oregon Medical School. • Read before the Fifty-fifth Annual MeetiRf, of Ore- f~r9.State Medical Society, La Grande, are., ay '16-18, •• Reference to several more cases has been noted. They are not included in Table I and bibliography due to failure to obtain original references. • lormed "bilateral salpingectomy, left oophorectomy, resec- tion of fundus of uterus to just below where tubes come off, removal of cone shaped piece from endomertium." Three drains were inserted to the cuI de sac. The patient was discharged twenty-four days after opera- tion with serous drainage from the incision. Menstruation occurred at the usual intervals and showed no notable ab- normality until the sixth month following operation, at which time the serous discharge from the incision hadI I I I I ~ Brit. Med. Jour., Legneu: Presse med., 1896, 289. Lenhossek: Anatomischer Anzeiger, 1845. Lexer: Arch. f. klin. Chir., 1894, xlviii, 410 Medical-Dental Bldg. (43) Keyes, E. L. Collings, C. W., and Camp- bell, M. F., J. Urol., vi, 519. (44) Landau: Muenchen Med. Wchnschr., 1905, No. 16. (45) LaPointe: A. La torsion du cord sperma. tique et l'infarct hemorragie du test, Paris: Ma- loine, 1904. (46) Lauentein: Samml. klin. Vortr., 1894, No. 92. (47) Le Conte: Internat. Clin., iv, 17th series, 1907. (48) (49) (50) 201. (51) Low: Brit. Med. Jour., 1906, May 26. (52) Lowden: Brit. Med. Jour., 1905, April 29, 932; Scotch Med. and Surg. Jour., ix, 229. (53) Lugones: Rev. assoc. med., argent., 1916,' xxv, 369. (54) Manson: Bull. med., 1902, 563. (55) McConnell: Dublin Jour. M. Soc., 1912, cxxxiii, 337. (56) Meyer, von: Deutsche.. med. Wchnschr., 1891, 800. (57) Moschkowitz: Ann. Surg., 1910, vii, 821. (58) Moschkowitz: Ann. Surg., June, 1912. (59) Murray: Brit. Med. Jour., 1912, ii, 7. (60) Nash: Brit. Med. Jour., 1893, 742. (61) Nicolandi: Arch. f. klin. Chir., 1885, xxxi, 182. (62) O'Connor: Surg., Gynecol. and Obstet., 1919, xxix, 580. (63) Odiorne and Simmons: Ann. Surg., 1904, 962. (64) Ormond: Ann. Surg., !<'ebruary, 1927. (64) Page:: Lancet., 1892, ii, 257. (66) Pearlman: Jour. Urol., 1927, xvii, 637. (67) Quadflieg: Deutsche med. Wchnschr., 1907, xxxiii, 2138. (68) Reboul: Rev. de chir., 1901, xxvi, 97. (69) Reizz: O. Gyogyaszat, Budapest, 1904, No. 44, 726. (70) Rigby and Howard: Lancet, 1907, i, 1416. (71) Robertson: ' Med. J. Australia, 1915, i, 213. (72) Sanders: Med. Miror, St. Louis, 1896, vii, 113. (73) Scheen: Lancet, 1896, i, 990. (74) Schiller: Wien, klin. Wchnschr., 1908, No. 18. (75) Scudder: Ann. Surg., xxxiv, 234. (76) Snyder: J. Kansas M. Soc., 1916, xvi, 195. (77) Spencer: Tr. Lond. Path. Soc., 1892, xliii, 51. (78) Stanton and Shaw: Albany M. Ann., 1904, August. (79) Stiles: Tr. Med. Chir. Soc., Edinburgh, 1906, Feb. 1. (80) Taylor: Brit. Med. Jour., 1897, Feb. 20. (81) Thorek: Interest. Med. Jour., xxvi, No. 3, 194. (82) Thorek: Ann. Surg., lxxxi, 1142. (83 Uffreduzzi: Arch. f. klin. Chir., 1912, c; 1913, ci, 159. (84) Van Der Pool: Med. Rec., 1800, 282. (85) :vanverts: Ann. d. mal, d. org. genito- urin, xxiii, 401. (86) Wallenstein, S.: J. Urol., 1929, xxi, 279. (87) Wendel: Muenchen. med. Wchnschr., 1908, 877. (88) Whipple and Nash: 1891, June 6, 1226. (89) Williams: Med. Fotrnightly, St. Louis, 1903, xxiv, 543. Brit. Med. Jour., 1893, ii, 13. Tr. M. Soc. Virginia, 1905, 402. Boston Med. and Surg. Jour., 1903, TORSION OF INTRO-ABDOMINAL TESTIS (1) Atherton: Med. Rec., 1901, lx, 816. (2) Atlee: Lancet, 1911, ii, 761. (3) Berg: Brit. Med. Jour., 1921, ii, 843. (4) Berg: Ann. Surg., August, 1904. (5) Berry: Birmingham M. Rev., 1898, 270. (6) Bevan: Arch. f. klin. Chir., lxxii, 1035. (7) Bevan: Jour. Amer. Med. Assoc., 1899, xxxiii, 773. (8) Bevan: Jour. Amer. Med. Assoc., 1903, xli, 718. (9) Brazil: (10) Bryan: (11) Cabot: cxlviii, 700. (12) Campbell: Meredith F., Surg. Gyn. and Obs. 1927 (March), 311. (13) Chevassu: Arch. gen. de chir., Par., 1908, ii, 225. (14) Corner: Clin. Jour., 1909-1904-1905, 202. (15) Cotte: Lyon med., 1911, cxvi, 758. (16) Cupler: Surg., Gynecol. and Obstet., 1915, xxi, 250. (17) Curling: Diseases of the Testis, 4th ed., 20. (18) Davis-Colley:: Brit. Med. Jour., 1892, Apr. 16, 811. (19) Delassiuave: Rev. Med. Franc. et etrang., 1840, 363. (20) De Quervain: Leut. Ztscher, f. chir., xli, 271. (21) Eccles: Lancet, 1902, i, 569. (22) Edington: Lancet, 1904, January 25, 1782. (23) Eitel: Northwest Lancet, 1905, xxv, 418. (24) Englische and Mayer: Wien. klin. Wchn schr., 1893, 603. (25) Farr: Ann. Surg., 1913, lxviii, 8138-852. (26) Finney: J. Roy, Army Med. Corps., Lond., 1914, xxii, 201. (27) Firth: Bristol Med. Jour., 1904, No. 86, 320. (28) Gerster: Ann. Surg., xxvii, 64. (29) Going and Keith: Lancet, 1906, 370. (30) Golding: Med. Rec., 1905, January 21, 98. (31) Gould, Pearce: Clin. Soc. Tr., xiv. 80. (32) Griffiths: Jour. Anat. and Physiol., 1896, xxx, 81. (33) Guiteras: Med. Rec., 1896, xlix, 11. (34) Halstead: Surg., Gynecol. and Obstet., 1907, iv, 129. (35) Howard: Brit. Med. Jour., 1907, ii, 719. (36) Howse: Royal College of Surgeon's Mu- seum Catalogue. (37) Jeffrey: Brit. Med. Jour., 1902, i, 1339. (38) Johnson: Ann. Surg., 1893, 282. (39) Johnson: H. A., Boston Med. and Surg. Jour., 1927, 1036. (40) Jordan: Leut. Med. Wchnscher., 1895, xxi, 525. (41) Keen: Tr. Roy. Med. and Chir. Sec., 1892, cclxxv, 25,3. (42) Kelly: Liverpool Med. and Chir. Jour., 1912, lxii, 394. and probably the necrosis and gangrene existing at operation, had so existed for several hours. Summary (1) A case of Torsion of the Sper- matic cord is reported. (2) The important features of such cases are summarized from the litera- ture. ! , , ~ .. '. I