SCREENING FOR MPD: CLINICAL UTILITY OF THE QUESTIONNAIRE OF EXPERIENCES OF DISSOCIATION GaryE. Dunn, Ph.D. Joseph J. Ryan, Ph.D. Anthony M. Paolo, Ph.D. Darrell M,S.W. Gary E. Dunn, Ph.D., is Staff Psychologist at the Dwight D. Eisenhower Veterans Administration Medical Center, in Leavenworth, Kansas. Joseph J. Ryan, Ph.D., is Chief of the Psychology Service at the Dwight D. Eisenhower Veterans Administration Medical Center. Anthony M. Paolo, Ph.D., is Assistan t Professor of Neurology at the University of Kansas Medical Center. Darrell Miller, M.S.W., is a Social Worker at the Johnson County Mental Health Center in Kansas. For reprints write: Gary E. Dunn, Ph.D., Psychology Service (116B) DDE VAMC, Leavenworth, Kansas 66048. ABSTRACT The major purpose of this study was to determine the effectiveness of the Questionnaire ofExperiences ofDissociation (QED) as a screen- ing instrument for the diagnosis of multiple personality disorder (MPD). The QED was administered to 18 patients with MPD, 18 control subjects, 18 alcoholics, and 15 patients diagnosed with both PTSD and a substance abuse disorder. Using a cut-off score of 15, the QED correctly identified all MPD patients as needing further screening. None of the control subjects, and only one of the alco- holics, were incorrectly identified as requiring further evaluation. These preliminary findings suggest that the QED has good clinical utility as a screening tool for the identification of individuals who are afflicted with multiple personality disorder. INTRODUCTION There is a need to screen for dissociative disorders, includ- ing multiple personality disorder, in psychiatric and sub- stance abuse populations. (Dunn, 1992) . The Questionnaire of Experiences ofDissociation (QED) (Riley, 1988) was devel- oped as a brief assessment technique for the study of disso- ciation. Riley reported that non-clinical populations aver- aged 9.92 points on the scale compared to 24.6 points for patients with multiple personality disorder (MPD) . However, the clinical utility of these scores was questionable since only three MPD patients were involved in the Riley study, and he omitted standard deviation and range statistics from the manuscript. Additionally, there was no information provid- ed regarding a cut-off score which practitioners might use to determine whether further evaluation of a dissociative disorder was indicated. The purpose of the present study was two-fold. First, we investigated the utility of the QED as a screening tool for multiple personality disorder. The second step involved the determination of a cut-off score that may be used to indi- cate the need for further assessment of a possible dissocia- tive disorder. METHOD Subjects Four groups of subjects were included in the present study. Group I (MPD) consisted of 18 individuals diagnosed as suffering multiple personality disorder. Of these, ten were receiving outpatient therapy at a midwestern community men- tal health center and eight were in therapy with a private practitioner. Each was diagnosed according to DSM-III-Rcri- teria. (American Psychiatric Association, 1987). Means and standard deviations for age and education were 37.00 years (SD=6.86) and 13.78 years (SD=2.64) , respectively. Fourteen patients were female (77.8%) and four were male (22.2%). Group II (control) consisted of 18 normal individuals living in the local community who were matched with the MPD patients on age, education, and gender. None had been treated for a psychiatric disorder. Means and standard devi- ations for age and education were 38.72 years (SD= 8.72) and 14.67 years (SD-2.09) respectively. Group III (alcoholics) consisted of 18 males being treat- ed for alcohol abuse, or alcohol dependence, on an inpa- tient unit in a midwestern Department of Veteran Affairs Medical Center. They were matched with the MPD and con- trol subjects on age and education. The means and standard deviations for age and education were 40.72 years (SD=4.64) and 13.33 years (SD=2.00), respectively. Group IV (PTSD) consisted of 15 patients, diagnosed, with post-traumatic stress disorder by a staff psychiatrist, using DSM-111R criteria. They were receiving inpatient treatment for a substance abuse problem at a midwestern Department of Veteran Affairs Medical Center. Fourteen were male (93.3%) and one was female (6.7%). Means and standard deviations for age and education were 43.40 years (SD=4.22) and 12.07 years (SD=1.87), respectively. A oneway analysis of variance indicated a significant age difference across the groups, F (3.65) - 2.98, p<.04. A Tukey post-hoc analysis revealed that the PTSD group was signifi- cantly older than the MPD group (43.40 vs 37.00, p, <.05). No other age differences emerged. However, oneway anal- ysis of variance revealed a significant difference in educa- tion across groups, F (3.65) = 4.46, p,<.Ol. A Tukey post- hoc analysis showed that the control subjects had significantly more years of schooling than the PTSD/substance abuse group, 38 DISSOCIATION, Col, VI, Na 1. Mardi 1993 DUNN/RYAN/PAOLO/MILLER TABLE 2 Sensitivity and Specificity Rates for Various QED Cut-off scores (MPD vs PTSD) (14.67 vs 12.07, p.<.05). No other differences were found. Instrument The Questionnaire of Experiences of Dissociation ( QED) (Riley, 1988) consists of 26 true-false items which were drawn from the clinical literature dealing with dissociative and mul- tiple personality disorders. As noted previously, normals pro- duced a mean score of 9.92 (SD=4.28) , while the mean score for three MPD patients was 24.6 (Riley, 1988). No cut-off scores have been developed to determine whether further assessment is needed to rule out a dissociative disorder. Procedure Subjects in the alcohol and PTSD groups completed the QED as part of the routine psychological evaluation done on the substance abuse unit between April, 1991 and November, 1992. The MPD subjects were in psychotherapy with one of the authors (D.M.) and agreed to complete the screening instrument for research purposes during the fall of 1992. Control subjects, who lived in the same metropoli- tan area as those with MPD, also agreed to complete the QED for research pur- poses during the fall of 1992. MPD and control subjects completed a demo- graphic sheet and signed a consent form. To make the QED a functional instrument for the clinician, it was important to establish a meaningful cut- off score for determining whether fur- ther assessment of a dissociative disorder was warranted. Similarly to the method employed by Steinberg, Rousaville and Cichetti (1991) with the DES, the pre- sent procedure was to maximize sen- sitivity: the ability to correctly identify true positive cases of dissociative dis- orders, and maximize specificity; and the ability to correctly identify persons without a dissociative disorder. In this way, false positive cases would be min- imized and fewer cases of true disso- ciative disorders would be missed. A number of QED values were tested in order to determine the most optimal score. RESULTS Means and standard deviations on the QED are presented in Table 1. A oneway analysis of variance indicated a significant difference across groups, F (3.65) = 46.11, p_<.0005. A Tukey post-hoc analysis demonstrated that MPD subjects achieved a higher mean score than the other groups, and that the PTSD group achieved a higher score than the alcohol or control groups (p_<.05). No other significant differences were found. Inspection of the score distributions of the four groups revealed no overlap between the MPD and controls, and only one person overlapped between the MPD and alcohol group when using a cut-off score of> 15. Substantial overlap of the distributions occurred between the MPD group and PTSD groups. Therefore, the score of> 15 points maximized sen- sitivity and specificity between the MPD group and the con- trol and alcohol groups. Thus, it was decided that a score of 15 or greater was the optimal cut-off. Using a cut-off score of > 15, the QED classified all 18 MPD subjects as needing further evaluation for a dissocia- tive disorder. Each of the 18 control subjects were classified as not being in need of further evaluation. Seventeen of 18 alcoholics (94.4%) and 9 of 15 PTSD subjects (60%) achieved QED scores which indicated that further evaluation was not warranted. Contrasting MPD and controls, a cut-off of 15 correctly classified all subjects resulting in 100% sensitivity and speci- TABLE 1 Means, Standard Deviations, and Ranges of QED scores by Diagnostic Group Mean SD Range MPD 21.06 3.56 15.00 - 26.00 Control 6.33 2.74 2.00 - 11.00 Alcoholic 6.33 3.68 0.00 - 15.00 PTSD 13.33 4.30 6.00 - 22.00 Cut Off Score Sensitivity Specificity 15 100% 60.0% 16 94.4% 66.7% 17 83.3% 73.3% 18 83.3% 86.7% 19 66.7% 86.7% 39 DISSOCIATION. Vol. VI, March199 3 SCREENING FOR MPD ficity. For MPD versus alcoholics, 100% sensitivity and 94.4% specificity was achieved. Using 15 as a cut-off score, a com- parison of the MPD and PTSD subjects resulted in 100% sen- sitivity and 60% specificity. Table 2 presents sensitivity and specificity results for additional QED cut-off scores in com- paring the MPD and PTSD groups. Contrasting the MPD sub- jects with all non-MPD subjects combined, a cut-off score of 15 resulted in 100% sensitivity and 86.3% specificity, with an overall hit rate of 89.8%. DISCUSSION The present study indicates that the QED has potential as a screening device for MPD, given its ease of administra- tion, response format, and brevity. Using a cut-off score of 15, all MPD subjects were classified as needing a more for- mal diagnostic evaluation for the presence of a dissociative disorder. To further support its effectiveness, the QED was able to correctly classify 100% of control subjects and over 94% of alcoholics as not being in need of additional evalu- ation. When the entire sample is dichotomized into MPD versus non-MPD subjects, the overall hit rate for the QED is approximately ninety percent. In regard to the PTSD group, the QED indicated that 40% of the subjects required further evaluation. This find- ing is not problematic, however, and may actually strength- en the credibility of the QED as a screening instrument for dissociative disorders. Previous research found significant dissociative experiences among patients diagnosed with PTSD (Bernstein & Putnam, 1986; Branscomb, 1991; Bremner et al, 1992). Furthermore, there is some evidence to support re-classifying PTSD as a dissociative disorder (Davidson & Foa, 1991). Several limitations should be noted regarding the pre- sent study. First, demographic variables were not equivalent across all groups. The PTSD group was approximately six years older, on average, in comparison to the MPD group. They also averaged about two and a half years less educa- tion in comparison to the control group. Finally, gender was not equivalent across the groups. While the MPD and con-tr ol groups each included 14 females and four males, the alcoholic group was entirely male and the PTSD abuse group had only one female. It is possible that these demographic differences skewed the overall results. For example, the preva- lence rate of multiple personality disorder is considered, by some experts, to be at least five times higher in females than males (Putnam, 1989). Thus, lower QED scores among the alcoholics and PTSD subjects may be a reflection, in part, of the gender distribution of the samples. However, other noted authorities have hypothesized that the actual male to female ratio of MPD in the general population is actually closer to one to one (Ross, 1989). Along the same lines, age dispari- ties in the groups may have contributed to QED differences given that dissociative experiences have been found to decline with age (Ross, Joshi, & Currie 1990). A second limitation is that the PTSD group was not pure. It consisted of indi- viduals who were being treated for some type of substance abuse and had a history of PTSD. It is unclear as to what the outcome would have been if individuals with a primary diag- nosis of PTSD would have been included. Another limitation is the inflated sensitivity and speci- ficity values due to a base rate of approximately 50% for the majority of analyses. Although an adequate hit rate was demon- strated when all groups were combined (base rate of 26%), the utility of the QED would certainly be reduced as base rates become lower. However, one study revealed a base rate of 39% for dissociative disorders in a substance abuse pop- ulation (Ross, et al., 1992), suggesting that a base rate of 26% may not be too unusual for some populations. Nevertheless, it would be beneficial to attempt to repli- cate these findings in a population where base rate of dis- sociative disorders, as well as other psychiatric syndromes, more closely approximate those found in other treatment settings. Finally, further research is needed using the QED with a more balanced sample of males and females within various diagnostic groups. CONCLUSION Despite the noted limitations, results of the present study indicate that the QED may be used as a screening tool for multiple personality disorder. Using a score of 15 as a cut- off, it was able to effectively distinguish patients with MPD from normals and alcoholics. If one considers PTSD as a pos- sible dissociative disorder the current findings support the use of the QED to screen for dissociative disorders. Further research is needed to replicate these findings as well as to test the QED with other diagnostic groups. Additionally, future studies are needed to determine if different QED norms exist based on geographic location, ethnicity, socio-economic status. etc. Finally, comparative studies, using the DES and QED may prove important in terms of their relative effectiveness as a screening instru- ment with various diagnostic groups. 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