Browsing by Author "Doe, Chris"

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A Developmental Framework for Coupling Neurogenesis to Circuit Formation in Drosophila

Mark, Brandon (University of Oregon, 2020-02-27)

Two central questions in neuroscience are how the brain is capable of both generating the diversity of neurons necessary for generating appropriate behaviors and how developmental programs are capable of then wiring these ...
Developmental Determinants of Neuronal Identity in the Drosophila Embryo

Seroka, Austin (University of Oregon, 2022-05-10)

The complex function of the nervous system is dependent on precise connectionsbetween hundreds of thousands of diverse neurons. During development, a small pool of neural progenitors is tasked with quickly generating this ...
Eyeless Leads the Way: Engineering a Neuronal Circuit for Navigation in Drosophila

Sullivan, Luis (University of Oregon, 2019-09-18)

The insect central complex (CX) is a conserved brain region containing 60+ neuronal subtypes, several of which contribute to navigation. It is not known how CX neuronal diversity is generated or how developmental origin ...
Intercellular Interactions Promoting Neural Circuit Formation and Function

Heckman, Emily (University of Oregon, 2022-10-26)

The function of the nervous system – from perception to behavior - relies on the orderlyformation of neural circuits during development. Given that there are billions of neurons in the human brain, and thus billions of ...
Molecular Origins of the Pair1 and Moonwalker Descending Neuron's Neural Circuitry in Drosophila

Linskens, Amanda; Lee, Kristen (University of Oregon, 2021)

During Drosophila development, neuroblasts produce neurons that acquires their identity based on the temporal transcription factor (tTF) present during birth. Although research shows that tTFs generate diversity, few have ...
Regulation of Drosophila Neural Circuit Assembly by Cell Surface Molecules

Sales, Emily (University of Oregon, 2020-02-27)

Nervous systems assemble with remarkable organization and precision. Developmental mechanisms ensure that neurons identify and form specific synapses with the correct set of neurons at the appropriate subcellular locations. ...
Stem Cell Self-renewal and Neuronal Differentiation in the Drosophila Central Nervous System

Carney, Travis (University of Oregon, 2013-10-03)

The adoption and subsequent retention of distinct cellular fates upon cell division is a critical phenomenon in the development of multicellular organisms. A well-studied example of this process is stem cell divisions; ...