Browsing by Subject "Muscleblind (MBNL1)"

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Contribution of Muscleblind-Like1 (MBNL1) Binding Events to Dose-Response Behavior of MBNL1

Gupta, Riti (University of Oregon, 2013-06)

Mis-regulation of the alternative splicing factor muscleblind-like I (MBNL 1) plays a significant role in the disease myotonic dystrophy (OM). MBNL 1 regulates alternative splicing of genes involved in development of ...
Investigating the RNA Binding Domains of MBNL1 and the Alternative Splicing Motifs They Recognize

Purcell, Jamie (University of Oregon, 2012)

Muscleblind-like 1 (MBNL1) is a ubiquitously expressed RNA binding protein that regulates the alternative splicing of a variety of transcripts. In Myotonic Dystrophy (DM) aberrant cellular localization of MBNL1 results in ...