Browsing by Author "Pluth, Michael"

Navigation

Display Options

Results

Now showing items 1-14 of 14

Binding of Hydrogen Sulfide to biologically relevant scaffolds: Metal systems and non-covalent binding

Hartle, Matthew (University of Oregon, 2017-05-01)

Hydrogen Sulfide (H2S) is an important biologically produced gasotransmitter along with carbon monoxide (CO) and nitric oxide (NO). Unlike CO and NO, the bioinorganic chemistry of H2S reactivity with biologically relevant ...
Design, Synthesis and Properties of Diindeno-Fused Acenes: Open-Shell Compounds for Organic Electronic Applications

Rudebusch, Gabriel (University of Oregon, 2016-10-27)

The consequence of free electrons in organic compounds has intrigued chemists for over a century. The fundamental idea of a covalent bond, a pair of electrons in a lasting attraction, and the localized spin of traditional ...
Developing and Utilizing Chemical Tools to Probe the Nature of Biological Sulfur Species

Bolton, Sarah (University of Oregon, 2021-11-23)

Life on Earth has always been shaped by sulfur. Over 2 billion years ago, before our atmosphere became rich in oxygen, volcanic activity was more prevalent. As a result, sulfur-containing gasses were much more prominent ...
Development of Chemical Tools for Delivery of Hydrogen Selenide to Biological Environments

Newton, Turner (University of Oregon, 2022-10-26)

Hydrogen selenide (H2Se) is the central species in the selenium metabolic cycle, sitting at the crossroads of protein-synthetic and excretory pathways. Despite its importance in biology and potential for therapeutic ...
Development of Chemical Tools for Studying Reactive Sulfur Species

Cerda, Matthew (University of Oregon, 2020-09-24)

Hydrogen sulfide (H2S) has recently emerged as an important biological signaling molecule involved in a number of key physiological processes. These observations have generated interest in harnessing H2S as a potential ...
Development of Tools for Understanding Biological Sulfur Chemistry

Bailey, Thomas (University of Oregon, 2016-10-27)

Hydrogen sulfide (H2S) is an important biomolecule for its role in mediating redox homeostasis and signaling biological processes. The study of biological sulfide is currently impeded by a lack of tools available that ...
Expanding the Sulfur Chemical Toolbox: Synthesis and Study of Small Molecule Carbonyl Sulfide Donors and Hydrogen Sulfide Probes

Levinn, Carolyn (University of Oregon, 2021-04-29)

Hydrogen sulfide (H2S) has recently been recognized as an important biological signaling molecule, with roles in regulating many biological processes, including neuromodulation and inflammation, as well as many disease ...
Heteroatom Substitution within Indenofluorenes

Marshall, Jonathan (University of Oregon, 2016-10-27)

The inclusion of atoms other than carbon into the framework of polycyclic conjugated hydrocarbons can have profound effects on the properties of the resultant compounds. Substitution of acenes with nitrogen-, oxygen-, and ...
Reactivity and Coordination Chemistry of Pnictogen-Containing Complexes

Collins, Mary (University of Oregon, 2016-02-23)

Only within the last decade has supramolecular chemistry begun to adopt the Group 15 elements into its field of research. This dissertation presents a supramolecular approach to the self-assembly and reactivity of Group ...
Self-Immolative Thiocarbamates for Studying COS and H2S Chemical Biology

Steiger, Andrea (University of Oregon, 2019-04-30)

In recent years, hydrogen sulfide (H2S) has garnered interest as the third addition to the gasotransmitter family. Essential to human physiology, H2S has roles in the cardiovascular, nervous, and respiratory systems and ...
Synthesis and Explorations of Indenofluorenes and Related Molecules

Rose, Bradley (University of Oregon, 2014-09-29)

Small perturbations upon the bonding of polycyclic conjugated hydrocarbons (PCH) lead to drastic changes of the properties. Despite being extensively studied for decades, there are numerous variants that remain unknown. ...
Targeted Delivery of Hydrogen Sulfide: Synthesis and Application of Small Molecule Hydrogen Sulfide Donors

Gilbert, Annie (University of Oregon, 2022-10-04)

Hydrogen sulfide (H2S) is an important gaseous signaling molecule that is endogenously produced. Over the past couple of decades, several biological functions of H2S have been recognized, including the ability of H2S to ...
The Development of Fluorescent Probes and Slow-Releasing H2S Donors for Studying Biological H2S

Hammers, Matthew (University of Oregon, 2016-10-27)

Hydrogen sulfide (H2S) is an essential small molecule in human physiology. Although quite toxic, H2S is produced endogenously and performs important regulatory functions in the cardiovascular, immune, nervous, and respiratory ...
Using Kinetics to Study the Stabilization of Reactive Hydrosulfide by Supramolecular Receptors

Longnight, Faith; Fargher, Hazel (grad mentor); de Faria, Thaís (grad mentor) (University of Oregon, 2021)

Hydrosulfide (HS-) has numerous biological and physiological implications given its roles as the third endogenously produced gasotransmitter. However, HS- is extremely reactive making it difficult to study. In this work, ...