The phosphorylation activity of protein kinases is involved in virtually all biological processes of living organisms. As uncontrolled kinase cascades cause devastating defects such as cancer, cells employ complex regulatory ...

As in many organisms, Caenorhabditis elegans oocytes assemble bipolar meiotic spindles in the absence of centrosomes. While the assembly of the mitotic spindle in C. elegans has been studied in some detail, how the poles ...