Browsing by Subject "Heart development"

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The regulation of alternative splicing associated with Myotonic Dystrophy

Warf, Michael Bryan (University of Oregon, 2009-09)

Myotonic Dystrophy (DM) is a genetic disorder with multisystemic symptoms that is caused by expression (as RNA) of expanded repeats of CTG or CCTG in the genome. It is hypothesized that the protein MBNL1 (M[barbelow]uscl ...
The Role and Regulation of Vascular Endothelial Growth Factor in Heart Development

Jones, Amy E. (University of Oregon, 2014-06)

The most common birth defects are due to malformations that occur during the development of the heart. The valves, trabeculae, and surrounding vasculature are all targets for molecular mishaps that can lead to lethality ...