Browsing by Subject "Arp2/3 Complex"

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Developing Biochemical Probes for a Required Activation Step of Arp2/3 Complex

Yoon, Dar (University of Oregon, 2016-05)

The Arp2/3 complex is a branched actin filament nucleator consisting of seven protein subunits. The Arp2/3 complex plays a crucial role in dynamic actin assembly, which is required for important cellular processes such ...
Mechanisms of Branched Actin Network Formation through Coordinate Activation of Arp2/3 Complex

Helgeson, Luke (University of Oregon, 2015-01-14)

Fundamental cellular processes such as motility and endocytosis rely on the actin cytoskeleton to translate biochemical protein interactions into mechanical forces. Cells utilize an extensive collection of actin binding ...
The Effects of WISH/DIP/SPIN90 and WASp Family Proteins Regulation of Arp2/3 Complex on Actin Network Architecture and Dynamics

Balzer, Connor (University of Oregon, 2020-09-24)

Actin-related protein (Arp) 2/3 complex is required to nucleate branched actin networks necessary for numerous cellular processes including cell motility and endocytosis. To nucleate branched actin filaments, Arp2/3 complex ...