Bacterial Secreted Protein GbpA Increases Cell Proliferation in the Drosophila Midgut

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Date

2018-06

Authors

Wong, Zoƫ Clare

Journal Title

Journal ISSN

Volume Title

Publisher

University of Oregon

Abstract

Both commensals and pathogens alike have innovated host-adapted survival strategies throughout the struggle to maintain evolutionary relevance. Successful microbes have found ways to build symbiotic relationships and hosts have similarly been conditioned to develop the means to benefit from, or at the very least tolerate, their associated microbes. In ever-changing environments like the gastrointestinal tract, high selective pressures call for bacterial-host interactions that contribute to homeostasis. In the intestine, maintaining healthy conditions depends on a careful balancing act between cell proliferation and cell death.

Description

42 pages. Presented to the Department of Biology and the Robert D. Clark Honors College in partial fulfillment of the requirements for the degree of Bachelor of Science June 2018

Keywords

Biology, Psychology, Molecular Biology, Microbiota, Drosophila Midgut, GbpA, Secreted Proteins, Cell Proliferation, Bacterial-Host Interactions

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