JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing by Subject "Molecular biology"
Navigation
Display Options
Results
Now showing items 1-20 of 20
-
(University of Oregon, 2008-09)Cellular polarity is a biological mechanism that is conserved across metazoa and is used in many different biological processes, one of which is stem cell self-renewal and differentiation. Stem cells generate cellular ...
-
(University of Oregon, 2011-12)This dissertation describes research into microbial influences on host signaling in the zebrafish intestine. Vertebrate organisms are consistently exposed to microbes, especially on epithelial tissues that are exposed to ...
-
(University of Oregon, 2011-09)Regulation of stem cell self-renewal versus differentiation is critical for embryonic development and adult tissue homeostasis. Drosophila larval neuroblasts divide asymmetrically to self-renew and are a model system for ...
-
(University of Oregon, 2009-06)Non-muscle myosin II generates contractile forces for processes such as cytokinesis, motility, and polarity. Contractility requires assembly of myosin molecules into bipolar mini-filaments through electrostatic interactions ...
-
(University of Oregon, 2011-12)The evolutionary history of protein families can be difficult to study because necessary ancestral molecules are often unavailable for direct observation. As an alternative, the field of computational phylogenetics has ...
-
(University of Oregon, 2008-09)This thesis explores the origin and evolution of animal germ layers via evolutionary-developmental analyses of the GATA family of transcription factors. GATA factors identified via a conserved dual zinc-finger domain direct ...
-
(University of Oregon, 2011-06)The vacuolar proton-translocating ATPase (V-ATPase) is a multisubunit enzyme complex responsible for acidification of cellular organelles. The V-ATPase hydrolyzes ATP to pump protons across membranes to create an electrochemical ...
-
Functions of organelle-specific nucleic acid binding protein families in chloroplast gene expression (University of Oregon, 2009-12)My dissertation research has centered on understanding how nuclear encoded proteins affect chloroplast gene expression in higher plants. I investigated the functions of three proteins that belong to families whose members ...
-
(University of Oregon, 2010-06)A critical question for developmental biology is the mechanism by which cells make fate decisions. In the hematopoietic system, stem cells differentiate into several different cell types, but the mechanisms that affect ...
-
Identifying targets and function of the ubiquitin related modifier Urm1 in Saccharomyces cerevisiae (University of Oregon, 2009-09)Post-translational modification of proteins is an important cellular method of controlling various aspects of protein activity, including protein-protein interactions, half- life, and transport. An important class of ...
-
(University of Oregon, 2011-06)Correct regulation of insulin/insulin-like growth factor signaling (IIS) is essential for proper development and growth. More recently, proper regulation of IIS has been shown to be important for adaptation and survival ...
-
(University of Oregon, 2016-06)Many bacteria live commensally in the intestines of complex host organisms. but the methods by which this community assembles are not fully understood. It is :i.uspected that two processes, inter-host dispersal and host ...
-
(University of Oregon, 2016-05)Gastrointestinal Brunner's Glands are composed of secretory glandular epithelium and are located at the junction between the pylorus of the stomach and the duodenum of the small intestine. Brunner's Glands function by ...
-
(University of Oregon, 2009-09)Gene duplication underlies the evolution of many protein functions and is a known stimulus for molecular innovation. Many models exist to explain the maintenance of duplicate genes in the genome and the dynamics that drive ...
-
(University of Oregon, 2021-04-29)Platinum(II) chemotherapeutic agents represent a critical class of anticancer compounds. The clinical use of these compounds is limited by side effects and development of resistance. Despite these limitations, the three ...
-
(University of Oregon, 2016-06)Heterochromatin is a minimally transcribed, densely bundled complex of DNA and associated factors comprising large regions of the eukaryotic genome. It is essential for chromosome stability, genome integrity, gene ...
-
(University of Oregon, 2011-03)Cells convey information through signaling pathways. Distinct signaling pathways often rely on similar mechanisms and may even use the same molecules. With a variety of signals conveyed by pathways that share components, ...
-
(University of Oregon, 2011-06)Regulated acidification of intercellular organelles and vesicles is essential for many cellular processes, from basic metabolism and protein sorting to synapse function and developmental signaling. These diverse processes ...
-
(University of Oregon, 2008-12)Programmed cell death (PCD) is a critical process during development and maturity of vertebrates and invertebrates. Aberrations in PCD are responsible for numerous developmental abnormalities and diseases in humans. Cell ...
-
(University of Oregon, 2011-09)This dissertation describes research to elucidate the early steps in the process of synapse formation in the zebrafish spinal cord. One question is how presynaptic proteins are trafficked and recruited to nascent synapses. ...
Now showing items 1-20 of 20