dc.contributor.advisor |
Haley, Michael |
|
dc.contributor.advisor |
Johnson, Darren |
|
dc.contributor.advisor |
Pluth, Michael |
|
dc.contributor.author |
Longnight, Faith |
|
dc.contributor.author |
Fargher, Hazel (grad mentor) |
|
dc.contributor.author |
de Faria, Thaís (grad mentor) |
|
dc.date.accessioned |
2021-07-27T16:51:59Z |
|
dc.date.available |
2021-07-27T16:51:59Z |
|
dc.date.issued |
2021 |
|
dc.identifier.uri |
https://scholarsbank.uoregon.edu/xmlui/handle/1794/26443 |
|
dc.description |
1 page. |
|
dc.description.abstract |
Hydrosulfide (HS-) has numerous biological and physiological implications given its roles as the third endogenously produced gasotransmitter. However, HS- is extremely reactive making it difficult to study. In this work, we aim to analyze how the presence of stabilizing forces from a supramolecular receptor influences the kinetics of HS- in a nucleophilic aromatic substitution (SNAr) reaction within organic media. We hypothesize that the non-covalent interactions from the supramolecular receptor will stabilize and reduce the reactivity of HS-. We will use UV-Vis to monitor the reaction over time and create non-linearized plots to obtain kinetic information. This study can provide insight into how our bodies might stabilize HS- through non-covalent interactions and give us a better understanding of the behavior of this species in biological systems. |
en_US |
dc.format.mimetype |
application/pdf |
|
dc.language.iso |
en_US |
|
dc.publisher |
University of Oregon |
|
dc.rights |
CC BY-NC-ND 4.0 |
|
dc.subject |
Supramolecular Receptors |
en_US |
dc.subject |
Hydrosulfide |
en_US |
dc.subject |
Kinetics |
en_US |
dc.subject |
Chemistry |
en_US |
dc.subject |
Reactive |
en_US |
dc.title |
Using Kinetics to Study the Stabilization of Reactive Hydrosulfide by Supramolecular Receptors |
|
dc.type |
Presentation |
|
dc.identifier.orcid |
0000-0001-9802-7751 |
|