Browsing Undergraduate Works by Author "Nolen, Brad"

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  • Developing an In Vivo Assay for Quantitative Analysis of Arp2/3 Complex Inhibitors 
    Topping, Maisie; Narvaez Ortiz, Heidy
    Branched networks in the actin cytoskeleton are critical for a variety of cellular processes such as motility and endocytosis. New branched actin filaments are nucleated by Arp2/3 complex, and the deregulation of this ...
  • Investigating the role of NPFs in the Arp3ΔC phenotype 
    Kiemel, Jonathan; Rodnick-Smith, Max; Liu, Su-Ling; Nolen, Brad; Wagner, Andrew
    The Arp2/3 complex is an assembly of seven protein subunits that nucleates branched actin networks involved in cellular functions such as endocytosis. Previous work has determined the complex is intrinsically inactive, and ...

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