Lipid‑protein and lipid‑lipid interactions in cytochrome oxidase model membranes
| dc.contributor.author | Jost, P. C. | |
| dc.contributor.author | Capaldi, R. A. | |
| dc.contributor.author | Vanderkooi, G. | |
| dc.contributor.author | Griffith, O. H. | |
| dc.date.accessioned | 2016-05-25T23:06:41Z | |
| dc.date.available | 2016-05-25T23:06:41Z | |
| dc.date.issued | 1973 | |
| dc.description | 14 pages | en_US |
| dc.description.abstract | Two lipid environments are dete cted in membranous cyto chrome oxidase , using spin labeling techniques. This model membrane system consists of closed vesicular membranes formed spontaneou sly when the mem hr,jlne protein is isolated with its accompanying phospholipids. The data show both an immobili zed componen t, which is constant in amount , and a fluid componen t. Based on spectral analysis, the interpretation is that the bound component repre sents a single layer of lipid immobilized on the surface of the protein between the hydrophobic protein complex and the adjacent fluid bilayer regions. Maximal enzyme activity of this functional protein complex is attained when all of the bound sites are occupied , and above this level additional phospholipid (bilayer) has little or no effect on the enzyme activity . | en_US |
| dc.identifier.citation | Jost, P. C., Capaldi, R. A., Vanderkooi, G. & Griffith, O. H. (1973) Lipid‑protein and lipid‑lipid interactions in cytochrome oxidase model membranes. J. Supramol. Struc. 1, 269‑280. | en_US |
| dc.identifier.uri | https://hdl.handle.net/1794/19889 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Journal of Supramolecular Structure | en_US |
| dc.rights | Creative Commons BY-NC-ND 4.0-US | en_US |
| dc.title | Lipid‑protein and lipid‑lipid interactions in cytochrome oxidase model membranes | en_US |
| dc.type | Article | en_US |