Browsing OA-APC Award Fund Winners Works by Subject "Oocytes"

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  • Aging and sperm signals alter DNA break formation and repair in the C. elegans germline 
    Toraason, Erik; Adler, Victoria L.; Libuda, Diana E. (PLOS, 2022-11-07)
    Female reproductive aging is associated with decreased oocyte quality and fertility. The nematode Caenorhabditis elegans is a powerful system for understanding the biology of aging and exhibits age-related reproductive ...
  • Excess crossovers impede faithful meiotic chromosome segregation in C. elegans 
    Hollis, Jeremy A.; Glover, Marissa L.; Schlientz, Aleesa J.; Cahoon, Cori K.; Bowerman, Bruce; Wignall, Sarah M.; Libuda, Diana E. (Public Library of Science, 2020-09-04)
    During meiosis, diploid organisms reduce their chromosome number by half to generate haploid gametes. This process depends on the repair of double strand DNA breaks as crossover recombination events between homologous ...

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