Prions are a form of protein that can switch from their native conformation to one that can promote aggregation. This sometimes inhibits or changes their normal cellular function, causing phenotypic changes. The Garcia Lab ...

Prion proteins, although frequently associated with neurodegenerative diseases, are not universally harmful to cells. Instead, prions may serve as a beneficial epigenetic mechanism, allowing cells to alter their phenotype ...

Prions are primarily associated with fatal neurodegenerative diseases, such as Mad Cow disease and Creutzfeldt-Jakob disease. Recent evidence, however, suggests that prions also comprise an additional class of epigenetic ...