Browsing Chemistry Theses and Dissertations by Subject "RNA structure"

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The regulation of alternative splicing associated with Myotonic Dystrophy

Warf, Michael Bryan (University of Oregon, 2009-09)

Myotonic Dystrophy (DM) is a genetic disorder with multisystemic symptoms that is caused by expression (as RNA) of expanded repeats of CTG or CCTG in the genome. It is hypothesized that the protein MBNL1 (M[barbelow]uscl ...