Abstract:
Anion sensing is an integral field of research in order to regulate and detect high concentrations of anions that are harmful to the environment. A dominant field of anion sensing research is through the development of supramolecular receptors. Typically, a single receptor is designed to exhibit selectivity, affinity, and a response towards one particular anion. In an attempt to find an all-encompassing receptor, the Darren W. Johnson and Michael M. Haley collaborative lab has developed a wide library of receptors based on an arylethynyl bisurea scaffold. This research looks to provide a better understanding of the binding interactions and preferences of this scaffold, characterize and screen previously synthesized receptors, and work towards developing a sensing assay utilizing the library of receptor molecules of the Johnson/Haley Lab.
Description:
61 pages. A thesis presented to the Department of Chemistry and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2017